Aston Human Tissue and
Electrophysiology Laboratories
Using human brain tissue and realistic disease models to identify and explore new therapies for children with epilepsy.
Aston Human Tissue Laboratory
The Aston Human Tissue Laboratory is part of the College of Health and Life Sciences.
The Human Tissue Laboratory provides a vital testing ground for novel drug research development, and testing, as well as providing a vital insight into links between invasive and non-invasive brain function testing.
The Human Tissue Laboratory provides vital information for drug development in the treatment of the childhood epilepsy. Children with the most severe epilepsy syndromes may undergo neurosurgery to remove brain tissue that is causing seizures. The human tissue laboratory takes this tissue and records information from individual brain cells and small networks of cells, in order to test novel antiepileptic drugs and understand the mechanisms of epilepsy.
Aston Electrophysiology Laboratory
Our electrophysiology lab explores brain function in epilepsy, schizophrenia, and normal brains, with the view to understanding how neuronal networks adapt during different circumstances. We explore brain function at the level of whole brain (EEG), local networks, and individual cells and synapses, using techniques such as field recording, patch-clamp, and calcium imaging.
