Teaching Activity on the MPharm Programme
PH1405 (Module coordinator): Chromatographic drug analysis, orbitals and bondings, nomenclature and stereochemistry,
practical applications of pharmaceutical analysis.
PH3602: Gene therapy
PH3605: Chromatographic drug analysis.
Career History
- 1998-date School of Life & Health Sciences, Aston University.
- 1997-98 Post-doctoral Research Fellow, MRC Toxicology Unit, University of Leicester.
- 1995-96 Post-doctoral Research Assistant, UCL.
- 1991-95 PhD Student/Research Assistant, UCL.
- 1990-91 Research Assistant, UCL.
- 1987-90 Zhejiang University, Zhejiang, China.
- 1984-87 Zhejiang University, Zhejiang, China, MSc in organic chemistry.
- 1978-82. Zhejiang University, Zhejiang, China, BSc in chemistry.
Research Interests
- Development of novel methodologies for synthesis of modified nucleic acids and peptide nucleic acids, and their use as potential antisense therapeutic agents.
- Oxidative DNA damage.
- Therapeutic natural products and their derivatives.
- Development of novel reagents for organic synthesis.
Selected Recent Publications
R. Guo and Q Zheng (2005)
Chemical Synthesis of oligonucleotides containing (M + 4) guanine
Nucleosides, Nucleotides, and Nucleic Acids 24 (5-7) 1081 – 1083
Z-G. Le, Z-C. Chen, Y. Hu, Q. Zheng (2005)
Organic reactions in ionic liquids: Ionic liquid-promoted efficient synthesis of N-alkyl and N-arylphthalimides.
JOURNAL OF HETEROCYCLIC CHEMISTRY 42 (4) 735-737
Y. Hu, Z-C. Chen, Z-G. Le, Q, Zheng (2004)
Organic reactions in ionic liquids: Ionic liquid promoted Knoevenagel condensation of aromatic aldehydes with (2-thio)barbituric acid.
SYNTHETIC COMMUNICATIONS 34 4521-4529
Z-G. Le, Z-C. Chen, Y. Hu, Q. Zheng (2004)
[bmim]Br(3)as a new reagent for regioselective monobromination of arylamines under solvent-free conditions.
SYNTHESIS-STUTTGART 17 2809-2812
Y. Hu, Z-C. Chen, Z-G. Le, Q. Zheng (2004)
Organic reactions in ionic liquids: Gewald synthesis of 2-aminothiophenes catalyzed by ethylenediammonium diacetate
Synthetic Communications 34 3801-3806
Z-G. Le, Z-C. Chen, Y. Hu, Q. Zheng (2004).
Organic reactions in ionic liquids: A simple and highlyregioselective N-substitution of pyrrole.
SYNTHESIS-STUTTGART 1951-1954
Y. Hu, Z-C. Chen, Z-G. Le, Q. Zheng (2004)
N-alkylation of N-monosubstituted sulfonamides in ionic liquids.
ORGANIC PREPARATIONS AND PROCEDURES INTERNATIONAL 347-351
Y. Hu, Z-C. Chen, Z-G. Le, Q. Zheng (2004)
Organic reactions in ionic liquids: An efficient method for selective S-alkylation of 2-mercaptobenzothia(xa)zole with alkyl halides.
SYNTHETIC COMMUNICATIONS 2039-2046
Z. G. Le, Z.-C. Chen, Y. Hu, Q. Zheng (2004)
Organic reactions in ionic liquids: Ionic liquid-promoted efficient synthesis of N-alkyl and N-arylimides.
Synthesis-Stuttgart 995-998
Z. G. Le, Z.-C. Chen, Y. Hu, Q. Zheng (2004)
Organic reactions in ionic liquids: A simple highly regioselective or regiospecific substitutions of benzotriazole
Heterocycles 63 1077-1081
Z-G. Le, Z-C. Chen, Y. Hu, Q. Zheng (2004)
Organic reactions in ionic liquids: N-alkylation of phthalimide and several nitrogen heterocycles.
Synthesis -Stuttgart 2 208-212
Z. Liu, Z-C. Chen, Q. Zheng (2004)
Organic reactions in ionic liquids: Ionic liquid-accelerated nucleophilic substitution reaction of alpha-tosyloxyketones with potassium salts of aromatic acids.
Synthesis -Stuttgart 1 33-36
Zheng, Q., Wang, Y., Lattmann,E. (2003)
Introduction of structural diversity into oligonucleotides containing 6-thioguanine via on-column conjugation.
Tetrahedron, 59, 1925 -1932.
Wang, Y., Lattmann, E., Zheng, Q. (2003)
Preparation of 6-thioguanosine phosphoramidite for oligoribonucleotide synthesis.
Nucleosides, Nucleotides & Nucleic Acids, 22, 1247-1249.
Su, C., Chen, Z-C., Zheng, Q. (2003)
Organic reaction in ionic liquids: Knoevenagel condensation catalysed by ethylenendiammonium diacetate.
Synthesis, 4, 555-559.
Zheng, Q., Wang, Y., Lattmann, E. (2003)
Synthesis of S6-(2, 4-dinitrophenyl)-6-thioguanosine phosphoramidite and its incorporation into oligoribonucleotides.
Bioorganic & Medicinal Chemistry Letters 13 3141-3144
Su, C., Chen, Z.-C., Zheng, Q. (2003)
Organic reactions in ionic liquids: alkylation of Meldrum acid
Synthetic Communications 33 2817-2822
Cheng, D-P., Chen, Z.-C., Zheng, Q. (2003).
Hypervalent iodine in synthesis 90: A mild and efficient method for the iodination of pyrazoles.
Synthetic Communications 33 2671-2676
