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Professor Gavin Woodhall

Professor in Neuropharmacology

School of Life and Health Sciences
Aston University
Aston Triangle
Birmingham
B4 7ET
UK

email: g.l.woodhall@aston.ac.uk
telephone: +44 (0) 121 204 3995

Research Group

Molecular Biomedical Research

Research Centre

Aston Brain Centre

 Aston Research centre in CHildren and Young people's health(ARCHY)


Member of the Pharmacy and Biology Teaching Programmes
PG Programme Director - MSc Pharmacology

Gavin Woodhall
Gavin Woodhall

PH2501: Antidysrhythmic drugs.
PH3601: Glutamate, drug abuse, epilepsy, general aAnaesthetics, learning and memory, excitotoxicity.
PH4705: Neuronal networks.

  • 1998–2002 Post-doctoral researcher, University of Bristol.
  • 1995–1998 Postdoctoral fellow University of Montreal, Canada.
  • 1994–1995 Postdoctoral Fellow University of Southampton.
  • 1991–1994 PhD University of Southampton  

Electrophysiological studies on neurones of the entorhinal cortex (EC).

The role of presynaptic metabotropic glutamate and NMDA receptors in epilepsy in the EC

The role of cannabinoids in the EC

The role of primary motor cortex in epilepsy and Parkinson’s disease (in collaboration with Dr. Ian Stanford and Dr. Stephen Hall).

The EC is part of the temporal lobe, a brain region which is especially prone to epilepsy. My research focuses on how epilepsy leads to changes the presynaptic control of neurotransmitter release onto neurones in the deep and superficial layers of the EC, and on the relationship between control of action potential evoked and action potential independent release of glutamate and GABA. I am also interested in the role of presynaptic CB1 cannabinoid receptors in control of GABA release in the normal and chronically epileptic EC. I am currently setting up a human tissue laboratory to investigate these questions in human brain slices.

I am also interested in primary motor cortex (M1), and am currently investigating neuronal network oscillations in this area, with a view to understanding how activity in M1 is altered through synaptic plasticity in epilepsy and Parkinson’s disease. These experiments are complemented by investigations in man via MEG studies (Steve Hall).

Dr. Roland Jones (University of Bath)

Wellcome Trust

£213k

2001-2005

Glutamate Induced Glutamate release in medial entorhinal cortex

Royal Society

£15k

2005-6

Synaptogenesis following epileptogenesis in the rat medial temporal lobe

Wellcome Trust

£262k

2008-11

Chronic changes in presynaptic function following epileptogenesis in the rat medial temporal lobe

NC3R/MRC

£152k

2007

Development of a reduced severity epilepsy model in the rat

ReGen

£46.5k

2007

Effects of Zolpidem and other ligands on spontaneous inhibitory postsynaptic currents and intenruonal oscillatory activity

ReGen

£18k

2007

MEG analysis of the cognitive effects of zolpidem

Recent Publications