School of Life and Health Sciences
Birmingham B4 7ET
Telephone: +44 (0) 121 204 5163
Room number: mb357
My research interests are in the improvement of existing methods and development of newbiomarkers to aid analysis of samples (for example identification of disease onset/progression or detection of contaminants such as bacteria and viruses).
My current project entitled “Promoting Biomarker Development in West Midland SMEs” aims to assist West Midland Small and Medium Enterprises (SMEs) to develop sophisticated and innovative biomarker technologies for their given field. The use of biomarkers will allow for quicker analysis with increased sensitivity whilst reducing overall costs, thereby increasing SME competitiveness.
The project is supported by funding from the European Regional Development Fund (ERDF) which is managed by the Department for Communities and Local Government (DCLG), funding received from ERDF is matched by Aston University.
More information on this project can be found in Aston University press releases, by contacting me directly or via the following contacts.
ERDF Biomarker project team:
Professor Helen Griffiths (Project Manager)
Professor Andy Pitt (Deputy Project Manager)
Dr Anthony Hilton (Specialist Scientific Advisor)
Dr Corinne Spickett (Specialist Scientific Advisor)
Qualifications and Education
2007 BSc with First Class Honours in Applied and Human Biology, Aston University
2012 PhD in Cell Biology, Aston University
Augustyniak, E., Adam, A., Wojdyla, K., Rogowska-Wrzesinska, A., Willetts, R.S., Korkmas, A., Atalay, M., Weber, D., Grune, T., Borsa, C., Gradinaru, D., Bollineni, R.A., Fedorova, A. & Griffiths, H.R. Validation of protein carbonyl measurements; a multi-centre study. Redox Biology
Marshall, L.J., Oguejiofor, W., Willetts, R.S., Griffiths, H.R. & Devitt, A. Developing accurate models of the human airways. Journal of Pharmacy and Pharmacology.
Griffiths, HR., Dias I.H., Willetts, R.S. & Devitt, A. (2014). Redox regulation of protein damage in plasma. Redox Biology, 20(2); 430-435
Torr, E.E., Gardner, D.H., Thomas, L., Goodall, D.M., Bielemeier, A., Willetts, R., Griffiths, H.R., Marshall, L.J. & Devitt, A. (2012). Apoptotic cell-derived ICAM-3 promotes both macrophage chemoattraction and tethering of apoptotic cells. Cell Death and Differentiation. 19(4); 671-679
Li, L., Willets, R.S., Polidori, M.C., Stahl, W., Nelles, G., Sies, H. & Griffiths, H.R. (2010). Oxidative LDL modification is increased in vascular dementia and is inversely associated with cognitive performance. Free Radical Research, 44(3); 241-248
Griffiths, H.R., Willetts, R.S., Grant, M.M., Mistry, N., Lunec, J. & Bevan, R.J. (2009). In vivo vitamin C supplementation increases phosphoinositol transfer protein expression in peripheral blood mononuclear cells from healthy individuals. The British Journal of Nutrition, 101(10); 1432-1439.