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Dr Manousos Klados

Lecturer in Biomedical Engineering

Department of Biomedical Engineering

School of Life & Health Sciences
Aston University
Birmingham, B4 7ET 

Phone number: +44 (0) 121 204 3740
Email: m.klados@aston.ac.uk
Personal Website: www.mklados.com
Room number: MB555

                             

Dr Manousos Klados

I joined Aston University in July 2017 as a Lecturer in Biomedical Engineering, having spent the previous 3 years in Germany as a research and teaching fellow at the Technical University of Dresden and postdoctoral researcher at Max Planck Institute for Human Cognitive and Brain Sciences, working on the field of Computational Neurosciences and Brain Networks. 

  • BSc in Mathematics, Aristotle University of Thessaloniki, 2007
  • MSc in Medical Informatics, Aristotle University of Thessaloniki, 2009
  • PhD in Medicine, Aristotle University of Thessaloniki, 2014
  • 2017 – date: Lecturer in Biomedical Engineering, School of Life and Health Sciences, Aston University
  • 2016 – 2017: Research and Teaching Fellow, Chair of Lifespan Developmental Neuroscience, TU Dresden, Germany
  • 2014 – 2016: Postdoctoral Researcher, Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany
  • 2007 – 2014: Research Assistant, School of Medicine, Aristotle University of Thessaloniki, Greece
BE1SE1 – Software Engineering

BE3MI1 – Medical Imaging

From a neuroscientific point of view, I am interested in affective neurosciences and mathematical cognition, where I am studying the impact of mathematical anxiety so in mental arithmetics as well as in pure working memory tasks. I am also working with neurofeedback, and it's potential application in neurovascular diseases. From a methodological perspective, my main research interests are based mostly on human connectivity, where I am currently investigating the connectivity phenotypes of personality using fMRI. I am also interested in graph theoretical modeling of human's brain, as well as the modulation introduced in brain networks either by affective and/or cognitive stimuli or under pathological circumstances

Society of Applied Neuroscience (SAN)

Institute of Electrical and Electronics Engineers (IEEE-EMB)

Max Planck Society

Hellenic Society of Neuroscience (HSN)

Federation of European Neuroscience Societies (FENS)

MENSA

International Federation for Medical and Biological Engineering (IFMBE)

European Alliance for Medical and Biological Engineering Science (EAMBES)

International Brain Research Organization (IBRO)

Hellenic Society of Biomedical Engineering (ELEVIT) 

  1. Klados, M. A., Gruzelier, J. H., & Bamidis, P. D. (Eds.). (2016). Biennial Meeting of the Society of Applied Neuroscience (SAN2016). Biennial Meeting of the Society of Applied Neuroscience (SAN2016). Frontiers Media SA. http://doi.org/10.3389/978-2-88919-993-8 (editor)

 

  1. Athanasiou, A., Klados, M. A., Pandria, N., Foroglou, N., Kavazidi, K. R., Polyzoidis, K., & Bamidis, P. D. (2017). A Systematic Review of Investigations into Functional Brain Connectivity Following Spinal Cord InjuryFrontiers in Human Neuroscience. Retrieved from https://www.frontiersin.org/article/10.3389/fnhum.2017.00517
  2. Klados, M. A., Pandria, N., Micheloyannis, S., Margulies, D., & Bamidis, P. D. (2017). Math anxiety: Brain cortical network changes in anticipation of doing mathematics. International Journal of Psychophysiology. http://doi.org/10.1016/j.ijpsycho.2017.05.003
  3. Pezoulas, V., Zervakis, M., Micheloyannis, S., & Klados, M. A. (2017). Resting-state functional connectivity and network analysis of cerebellum with respect to crystallized IQ and gender. Frontiers in Human Neuroscience. Retrieved from http://journal.frontiersin.org/article/10.3389/fnhum.2017.00189
  4. Jakobsen, E., Liem, F., Klados, M. A., Bayrak, Ş., Petrides, M., & Margulies, D. S. (2016). Automated individual-level parcellation of Broca’s region based on functional connectivity. NeuroImage. http://doi.org/10.1016/j.neuroimage.2016.09.069
  5. Klados, M. A., & Bamidis, P. D. (2016). A semi-simulated EEG/EOG dataset for the comparison of EOG artifact rejection techniquesData in Brief8, 1004–1006. http://doi.org/10.1016/j.dib.2016.06.032
  6. Athanasiou, A., Klados, M. A., Styliadis, C., Foroglou, N., Polyzoidis, K., & Bamidis, P. D. (2016). Investigating the role of alpha and beta rhythms in functional motor networks. Neuroscience. http://doi.org/10.1016/j.neuroscience.2016.05.044
  7. Klados, M. A., Styliadis, C., Frantzidis, C. A., Paraskevopoulos, E., & Bamidis, P. D. (2016). Beta-Band Functional Connectivity is Reorganized in Mild Cognitive Impairment after Combined Computerized Physical and Cognitive Training. Frontiers in Neuroscience10. http://doi.org/10.3389/fnins.2016.00055
  8. Klados, M. A., Simos, P., Micheloyannis, S., Margulies, D., & Bamidis, P. D. (2015). ERP measures of math anxiety: how math anxiety affects working memory and mental calculation tasks? Frontiers in Behavioral Neuroscience9. http://doi.org/10.3389/fnbeh.2015.00282
  9. Frantzidis, C. A., Vivas, A. B., Tsolaki, A., Klados, M. A., Tsolaki, M., & Bamidis, P. D. (2014). Functional disorganization of small-world brain networks in mild Alzheimer’s Disease and amnestic Mild Cognitive Impairment: an EEG study using Relative Wavelet Entropy (RWE). Frontiers in Aging Neuroscience6. http://doi.org/10.3389/fnagi.2014.00224
  10. Klados, M. A. (2014). Beyond the Clinical Use of Neurofeedback. Journal of Psychology & Clinical Psychiatry1(3). http://doi.org/10.15406/jpcpy.2014.01.00014
  11. Bamidis, P. D., Vivas, A. B., Styliadis, C., Frantzidis, C., Klados, M.A., Schlee, W., … Papageorgiou, S. G. (2014). A review of physical and cognitive interventions in aging. Neuroscience & Biobehavioral Reviews44, 206–220. http://doi.org/10.1016/j.neubiorev.2014.03.019
  12. Klados, M. A., Kanatsouli, K., Antoniou, I., Babiloni, F., Tsirka, V., Bamidis, P. D., & Micheloyannis, S. (2013). A Graph theoretical approach to study the organization of the cortical networks during different mathematical tasks. PloS One8(8), e71800. http://doi.org/10.1371/journal.pone.0071800
  13. Athanasiou, A., Lithari, C., Kalogianni, K., Klados, M. A., & Bamidis, P. D. (2012). Source Detection and Functional Connectivity of the Sensorimotor Cortex during Actual and Imaginary Limb Movement: A Preliminary Study on the Implementation of eConnectome in Motor Imagery Protocols. Advances in Human-Computer Interaction2012, 1–10. http://doi.org/10.1155/2012/127627
  14. Lithari, C., Klados, M. A., Papadelis, C., Pappas, C., Albani, M., & Bamidis, P. D. (2012). How does the metric choice affect brain functional connectivity networks? Biomedical Signal Processing and Control7(3), 228–236. http://doi.org/10.1016/j.bspc.2011.05.004
  15. Lithari, C., Klados, M. A., Pappas, C., Albani, M., Kapoukranidou, D., Kovatsi, L., … Papadelis, C. L. (2012). Alcohol Affects the Brain’s Resting-State Network in Social Drinkers. PLoS ONE7(10).
  16. Klados, M. A., Papadelis, C., Frantzidis, C., & Bamidis, P. (2011). Is the Artifact Rejection enhanced if the EOG signals are included in the ICA decomposition? Neuroscience Letters500, e50–e51. http://doi.org/10.1016/j.neulet.2011.05.216
  17. Moridis, C., Klados, M. A., Terzis, V., Economides, A., Karlovasitou, A., Bamidis, P., & Karabatakis, V. (2011). Audiovisual stimulation to influence alpha brain oscillations: An EEG study of gender differences. Neuroscience Letters500, e51. http://doi.org/10.1016/j.neulet.2011.05.217
  18. Frantzidis, C., Semertzidou, A., Ladas, A., Karagianni, M., Lithari, C., Kyrillidou, A., … Bamidis, P. (2011). Detecting neurophysiological alterations during Mild Cognitive Impairment and Dementia using wavelet-based energy computation and a Mahalanobis Distance classifier. Neuroscience Letters500, e53. http://doi.org/10.1016/j.neulet.2011.05.225
  19. Klados, M. A., Papadelis, C., Braun, C., & Bamidis, P. D. (2011). REG-ICA: A hybrid methodology combining Blind Source Separation and regression techniques for the rejection of ocular artifacts. Biomedical Signal Processing and Control6(3), 291–300. http://doi.org/10.1016/j.bspc.2011.02.001
  20. Frantzidis, C. A., Bratsas, C., Klados, M. A., Konstantinidis, E., Lithari, C. D., Vivas, A. B., … Bamidis, P. D. (2010). On the Classification of Emotional Biosignals Evoked While Viewing Affective Pictures: An Integrated Data-Mining-Based Approach for Healthcare Applications. IEEE Transactions on Information Technology in Biomedicine14(2), 309–318. http://doi.org/10.1109/TITB.2009.2038481
  21. Lithari, C., Frantzidis, C., Klados, M. A., & Bamidis, P. D. (2010). Does arousal and valence affect ERPs and brain connectivity? A study during an emotional paradigm. International Journal of Psychophysiology77(3), 266–266. http://doi.org/10.1016/j.ijpsycho.2010.06.101
  22. Lithari, C., Frantzidis, C. A., Papadelis, C., Vivas, A. B., Klados, M. A., Kourtidou-Papadeli, C., … Bamidis, P. D. (2010). Are females more responsive to emotional stimuli? A neurophysiological study across arousal and valence dimensions. Brain Topography23(1), 27–40. http://doi.org/10.1007/s10548-009-0130-5
  23. Klados, M. A., Frantzidis, C., Vivas, A. B., Papadelis, C., Lithari, C., Pappas, C., & Bamidis, P. D. (2009). A Framework Combining Delta Event-Related Oscillations (EROs) and Synchronisation Effects (ERD/ERS) to Study Emotional Processing. Computational Intelligence and Neuroscience2009, 1–16. http://doi.org/10.1155/2009/549419
  1. Klados, M.A., Lauckner, M., Jackobsen, E., & Daniel, M. (2016). Characterizing the Primary Spectrum of Personality and Brain Connectivity. In 22nd Annual Meeting of the Organization for Human Brain Mapping.
  2. Pezoulas, V., Zervakis, M., Micheloyannis, S., & Klados, M. A. (2016). Investigating the correlation between crystallized IQ and network metrics in cerebellum using resting-state fMRI. Frontiers in Human Neuroscience10. http://doi.org/10.3389/conf.fnhum.2016.220.00013
  3. Klados, M. A. (2016). Human Connectome as a big-data problem: New approaches for analysis and visualization.Frontiers in Human Neuroscience10. http://doi.org/10.3389/conf.fnhum.2016.220.00012
  4. Athanasiou, A., Klados, M. A., Astaras, A., Foroglou, N., Magras, I., & Bamidis, P. D. (2016). State of the Art and Future Prospects of Nanotechnologies in the Field of Brain-Computer Interfaces. In XIV Mediterranean Conference on Medical and Biological Engineering and Computing (pp. 456–460). Springer. http://doi.org/10.1007/978-3-319-32703-7_89
  5. Athanasiou, A., Klados, M. A., Foroglou, N., Klados, K. R., Polyzoidis, K., & Barnidis, P. D. (2016). Reorganization of brain networks after spinal cord injury: a qualitative synthesis of the literature. Frontiers in Human Neuroscience10. http://doi.org/10.3389/conf.fnhum.2016.220.00036
  6. Bayrak, Ş., Margulies, D., Bamidis, P., & Klados, M. A. (2016). Mathematical Anxiety influences the cortical connectivity profiles in lower alpha band during working memory tasks. Frontiers in Human Neuroscience10. http://doi.org/10.3389/conf.fnhum.2016.220.00001
  7. Jakobsen, E., Klados, M.A., Zelmer, J., Goulas, A., & Margulies, D. S. (2015). Automated individual-level parcellation of Broca’s region based on resting-state functional connectivity. In 21st Annual Meeting of the Organization for Human Brain Mapping (OHBM).
  8. Klados, M. A., Styliadis, C., & Bamidis, P. D. (2014). A Short Review on Emotional Recognition Based on Biosignal Pattern Analysis. In XIII Mediterranean Conference on Medical and Biological Engineering and Computing (pp. 787–790). http://doi.org/10.1007/978-3-319-00846-2_195
  9. Bamparopoulos, G., Klados, M. A., Papathanasiou, N., Antoniou, I., Micheloyannis, S., & Bamidis, P. D. (2014). Studying Functional Brain Networks to Understand Mathematical Thinking: A Graph-Theoretical Approach. In L. M. Roa Romero (Ed.), XIII Mediterranean Conference on Medical and Biological Engineering and Computing (Vol. 41, pp. 783–786). Springer International Publishing. http://doi.org/10.1007/978-3-319-00846-2_194
  10. Klados, M. A., Nikolaidou, M., Konstantinidis, E., Chifari, A., & Bamidis, P. D. (2013). A short review of computerized monitoring systems for ADHD. In Proceedings of the 26th IEEE International Symposium on Computer-Based Medical Systems (pp. 556–557). IEEE. http://doi.org/10.1109/CBMS.2013.6627875
  11. Klados, M. A., Lithari, C., Antoniou, I., Semertzidou, A., Bratsas, C., Micheloyannis, S., & Bamidis, P. D. (2012). Towards a graph theoretical approach to study gender lateralization effect in mathematical thinking. In 2012 IEEE 12th International Conference on Bioinformatics & Bioengineering (BIBE) (pp. 666–670). IEEE. http://doi.org/10.1109/BIBE.2012.6399746
  12. Frantzidis, C. A., Diamantoudi, M. D., Grigoriadou, E., Semertzidou, A., Billis, A., Konstantinidis, E., … Bamidis, P. D. (2012). A Mahalanobis Distance Based Approach towards the Reliable Detection of Geriatric Depression Symptoms Co-existing with Cognitive Decline. In L. Iliadis, I. Maglogiannis, H. Papadopoulos, K. Karatzas, & S. Sioutas (Eds.), Artificial Intelligence Applications and Innovations SE - 2 (Vol. 382, pp. 16–25). Springer Berlin Heidelberg. http://doi.org/10.1007/978-3-642-33412-2_2
  13. Artikis, A., Bamidis, P. D., Billis, A., Bratsas, C., Frantzidis, C., Karkaletsis, V., … others. (2012). Supporting tele-health and AI-based clinical decision making with sensor data fusion and semantic interpretation: The USEFIL case study. International Workshop on Artificial Intelligence and NetMedicine, 21.
  14. Klados, M. A., Bratsas, C., Frantzidis, C., Papadelis, C. L., & Bamidis, P. D. (2010). A Kurtosis-Based Automatic System Using Naïve Bayesian Classifier to Identify ICA Components Contaminated by EOG or ECG Artifacts. In XII Mediterranean Conference on Medical and Biological Engineering and Computing (pp. 49–52). http://doi.org/10.1007/978-3-642-13039-7_13
  15. Lithari, C., Klados, M. A., & Bamidis, P. D. (2010). Graph Analysis on Functional Connectivity Networks during an Emotional Paradigm. In XII Mediterranean Conference on Medical and Biological Engineering and Computing (pp. 115–118). Springer. http://doi.org/10.1007/978-3-642-13039-7_29
  16. Moridis, C. N., Klados, M. A., Terzis, V., Economides, A. A., Karabatakis, V. E., Karlovasitou, A., & Bamidis, P. D. (2010). Affective Learning: Empathetic Embodied Conversational Agents to Modulate Brain Oscillations. In XII Mediterranean Conference on Medical and Biological Engineering and Computing (pp. 675–678). http://doi.org/10.1007/978-3-642-13039-7_170
  17. Komnidis, A., Konstantinidis, E., Stylianou, I., Klados, M. A., Kalfas, A., & Bamidis, P. D. (2010). A Modular Architecture of a Computer-Operated Olfactometer for Universal Use. In XII Mediterranean Conference on Medical and Biological Engineering and Computing (pp. 280–283). http://doi.org/10.1007/978-3-642-13039-7_70
  18. Moridis, C. N., Klados, M. A., Kokkinakis, I. A., Terzis, V., Economides, A. A., Karlovasitou, A., … Karabatakis, V. E. (2010). The impact of audio-visual stimulation on alpha brain oscillations: An EEG study. In Proceedings of the 10th IEEE International Conference on Information Technology and Applications in Biomedicine (pp. 1–4). IEEE. http://doi.org/10.1109/ITAB.2010.5687651
  19. Frantzidis, C. A., Lithari, C. D., Klados, M. A., Pappas, C., & Bamidis, P. D. (2010). Synchronization analysis of short EEG data through time-evolving relative wavelet entropy and IAPS affective visual stimuli. In Proceedings of the 10th IEEE International Conference on Information Technology and Applications in Biomedicine (pp. 1–4). IEEE. http://doi.org/10.1109/ITAB.2010.5687646
  20. Peranonti, E. G., Klados, M. A., Papadelis, C. L., Kontotasiou, D. G., Kourtidou-Papadeli, C., & Bamidis, P. D. (2010). Can the EEG Indicate the FiO2 Flow of a Mechanical Ventilator in ICU Patients with Respiratory Failure? In XII Mediterranean Conference on Medical and Biological Engineering and Computing 2010 (pp. 827–830). Springer. http://doi.org/10.1007/978-3-642-13039-7_209
  21. Lithari, C., Frantzidis, C. A. A., Papadelis, C., Klados, M. A., Pappas, C., & Bamidis, P. D. D. (2010). Small-world properties of brain Functional Connectivity Networks are affected by emotional stimuli. In Proceedings of the 10th IEEE International Conference on Information Technology and Applications in Biomedicine (pp. 1–4). IEEE. http://doi.org/10.1109/ITAB.2010.5687815
  22. Bratsas, C., Frantzidis, C. A., Klados, M.A., Papadelis, C., Pappas, C., & Bamidis, P. D. (2009). Towards a semantic framework for an integrative description of neuroscience patterns and studies: a case for emotion-related data. Studies in Health Technology and Informatics150, 322–6. http://doi.org/10.3233/978-1-60750-044-5-322
  23. Klados, M. A., Papadelis, C., Lithari, C. D., & Bamidis, P. D. (2009). The Removal Of Ocular Artifacts From EEG Signals: A Comparison of Performances For Different Methods. In 4th European Conference of the International Federation for Medical and Biological Engineering (pp. 1259–1263). http://doi.org/10.1007/978-3-540-89208-3_300
  24. Bamidis, P. D., Frantzidis, C. A., Konstantinidis, E. I., Luneski, A., Lithari, C., Klados, M. A., … Pappas, C. (2009). An Integrated Approach to Emotion Recognition for Advanced Emotional Intelligence. In 13th International Conference of HCI International (pp. 565–574). http://doi.org/10.1007/978-3-642-02580-8_62
  25. Klados, M. A., Papadelis, C. L., & Bamidis, P. D. (2009). REG-ICA: A new hybrid method for EOG Artifact Rejection. In 2009 9th International Conference on Information Technology and Applications in Biomedicine (pp. 1–4). IEEE. http://doi.org/10.1109/ITAB.2009.5394295