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Dr Lindsay J Marshall

Dr Lindsay J Marshall profile

Lecturer in Immunology

School of Life and Health Sciences
Aston University
Aston Triangle
Birmingham B4 7ET
UK

email: l.marshall@aston.ac.uk
telephone: +44 (0) 121 204 4017
fax: +44 (0) 121 204 3892

Research Theme

Chronic and Communicable Conditions

Research Centre

Aston Research Centre for Healthy Ageing (ARCHA) 

Member of the Pharmacy and Biology Teaching Programmes

Teaching Activity on the MPharm Programme

PH2502: Immunology teaching 

Career History

2004-date Lecturer in Immunology, Aston University

2001-2004 Research Fellow, Portsmouth University

1998-2000 Research Fellow, Southampton University

1994-1998 PhD Cell Biology, University of Dundee

1993 MSc Experimental and Molecular Pathology, University of Dundee

1988-1992 BSc (Hons) Biology, University of Stirling

Research Interests

  • Mucosal immunology
  • Modelling the airways epithelium in vitro
  • Protein glycosylation in health and disease
  • Host-pathogen and pathogen-pathogen interactions

Recent Publications

  • Marshall, L.J., Perks, B., Bodey, K., Suri, R., Bush, A., and Shute, J. K. (2004) Free secretory component from cystic fibrosis sputa displays the CF glycosylation phenotype. Am. J. Respir. Crit Care Med. 169:3; 399-406.
  • Marshall, L.J., Ramdin, L.S.P., Brooks, T, Charlton, P., Shute, J.K. (2003) Plasminogen activator inhibitor-1 supports interleukin-8–mediated neutrophil transendothelial migration by inhibition of the constitutive shedding of endothelial IL-8/heparan sulphate/syndecan-1 complexes. J Immunol. 171:2057-2065.
  • J. K. Shute, L. J. Marshall, K. Bodey and A. Bush. (2003) Growth factors in cystic fibrosis: when more is not enough. Paediatr Respir Rev. 4(2):120-7.
  • R. Suri, L. J. Marshall, C. Wallis, C. Metcalfe, J. K. Shute and A. Bush (2003) Safety and use of sputum induction in children with cystic fibrosis. Pediatr Pulmonol. 2003. 35(4):309-13.
  • R. Suri, L. J. Marshall, C. Wallis, C. Metcalfe, A. Bush and J. K. Shute. (2002) Effects of recombinant human DNase and hypertonic saline on airway inflammation in children with cystic fibrosis. Am. J. Respir. Crit. Care Med. 166(3):352-5.
  • Marshall, L.J., Perks, B. Ferkol, T., and Shute, J.K. (2001) Interleukin-8 released constitutively by primary bronchial epithelial cells in culture forms an inactive complex with secretory component. J Immunol. 167:2816-2823.
  • Treharne K.J., Riemen C.E., Marshall L.J., Muimo R., Mehta A. (2001) Nucleoside diphosphate kinase--a component of the [Na(+)]- and [Cl(-)]-sensitive phosphorylation cascade in human and murine airway epithelium. Pflugers Arch. 443 Suppl 1:S97-102.
  • Marshall, L.J., Muimo, R., Reimen, C. E. and Mehta, A. (1999) Na+ and K+ regulate the phosphorylation state of nucleoside diphosphate kinase in human airway epithelium. Am J Physiol 276 (Cell Physiol 45): C109-C119.
  • Muimo, R., Banner, S.J., Marshall, L.J. and Mehta, A. (1998) Nucleoside diphosphate kinase and Cl- sensitive protein phosphorylation in apical membranes from ovine airway epithelium. Am J Respir Cell Mol Biol 18:2: 270-278.
  • Treharne, K.J., Marshall, L.J. and Mehta, A. (1994) A novel, chloride-dependent, GTP-utilising kinase in plasma membranes from human respiratory epithelium. Am J Physiol (Lung Cell Mol Biology) 267: L592-L601.

Employable Graduates; Exploitable Research