Aston University Aston TriangleBirmingham B4 7ETUK
Room: MB 341b Tel: +44 (0) 121 204 3077 Email: email@example.com
I have always had a strong interest in science and in particular human biology, health and disease and the associated interventions. My undergraduate degree in Human Biology mapped onto this interest and included molecular and cellular biology, biochemistry and physiology modules among others, which would carry relevance in the physiology and pharmacology setting I progressed into. I further developed my knowledge and bolstered my interest in these fields during my PhD. During this period, formulation of oral liquid antihypertensives formed the initial stages of my project; here an understanding of the chemical and physical properties of drug molecules as well as drug action on a molecular level in a physiological setting was essential. In vitro and In vivo characterisation of developed formulations utilising cell and rodent based models paved the way for subsequent genomic investigations into intestinal transporter expression profiling using microarray technology and bioinformatics. Cell culture played a key role during a spin off project which I have been developing in parallel with the main path of research which has seen the isolation and characterisation of a novel primary cell line aimed at delineation of gustatory sensation.
PH2502 – Pharmaceutical Microbio/Genomics/Genetics/Immunol (Module Coordinator)PH4701 – Clinical Pharmaceuticals and Drug DeliveryPHMCT3 – Pharmaceutics in PracticePHM014 – Drug Delivery and TargetingPHM3603 - Pharmaceutical Formulation III
BSc(Hons) Human Biology
August 2016 – Present: Lecturer in Pharmaceutics at Aston UniversityOctober 2014 – July 2016: Lecturer in Physiology and Pharmacology at Coventry University CollegeFebruary 2014 – June 2014: Lecturer in QbD at Aston UniversityJanuary 2014 – July 2014: Postdoctoral Researcher at Aston UniversitySeptember 2010 – December 2014: Studied PHD at Aston UniversitySeptember 2006 – June 2010: Studied BSc (Hons) Human Biology at Uni. Huddersfield
School Governor at Coppice Junior School Part Time Lecturer at Coventry University College
In my role as a lecturer in pharmaceutics I intend to further advance research into in vitro drug absorption modelling. The aim is to benefit the drug development pipeline through an innovative application of novel approaches to permeability assays including genomic and metabolomic approaches not currently exploited. If successful this holds promise to reduce the number of medicinal products which fail at late stage clinical trials thus saving significant time and money. Concurrently, process development seeks to enhance and advance the technologies and methodologies used in existing drug development areas on a day to day basis. With a focus on formulation the techniques and technologies employed in current research are at the cutting edge of formulation development. Solubilisation and stabilisation of insoluble and sensitive drugs for the formulation of oral liquid medications represents one line of research while elsewhere, recent advances in 3D printing technology and intelligent formulation design are currently being exploited to produce novel solid dosage forms targeting a personalised medicine approach to drug development.
Biochemical SocietyUnited Kingdom and Ireland Controlled Release Society (UKICRS)Associate member of the Physiological Society
Craig Russell, Sumyra Begum, Yasar Hussain, Majad Hussain, David Huen, Ayesha S Rahman, Yvonne Perrie and Afzal R Mohammed. (2015) Paediatric Drug Development of Ramipril: Reformulation, In Vitro and In Vivo Evaluation. Journal of Drug Targeting
Craig Russell, Ayesha Rahman and Afzal R Mohammed (2013) Application of genomics, proteomics and metabolomics in drug discovery, development and clinic. Therapeutic Delivery. 4 (3) 395 - 413.
Afzal R Mohammed and Craig A Russell (2012). Drug Development and Delivery. Integrated Foundations of Pharmacy – Pharmaceutics.
Afzal R. Mohammed, Amr M. ElShaer, Rhys J. Jones, Sheraz Khan, Craig A. Russell (2011) Drug Bioavailability and Gene Profiling: Challenges and Opportunities for Pharmaceutics and Personalised Medicine. Handbook of Personalized Medicine: Advances in Nanotechnology, Drug Delivery and Therapy.
Other PublicationsAffiong Iyire, Craig Russell, Clifford Bailey and Afzal R Mohammed (2014) Investigating buccal cell cultures to enhance assessment of transmucosal drug delivery. UKICRS newsletter.