Dr Craig Russell

Lecturer in Pharmaceutics

Third Year Tutor (MPharm)

School of Life & Health Sciences

Aston University
Aston Triangle
B4 7ET

Room: MB 341b
+44 (0) 121 204 3077
Email: c.russell6@aston.ac.uk

Craig Russell
Craig Russell

I have always had a strong interest in science and in particular human biology, health and disease and the associated interventions. My undergraduate degree in Human Biology mapped onto this interest and included molecular and cellular biology, biochemistry and physiology modules among others, which would carry relevance in the physiology and pharmacology setting I progressed into. I further developed my knowledge and bolstered my interest in these fields during my PhD. During this period, formulation of oral liquid antihypertensives formed the initial stages of my project; here an understanding of the chemical and physical properties of drug molecules as well as drug action on a molecular level in a physiological setting was essential. In vitro and In vivo characterisation of developed formulations utilising cell and rodent based models paved the way for subsequent genomic investigations into intestinal transporter expression profiling using microarray technology and bioinformatics. Cell culture played a key role during a spin off project which I have been developing in parallel with the main path of research which has seen the isolation and characterisation of a novel primary cell line aimed at delineation of gustatory sensation.

PH2502 – Pharmaceutical Microbio/Genomics/Genetics/Immunol  (Module Coordinator)
PH4701 – Clinical Pharmaceuticals and Drug Delivery
PHMCT3 – Pharmaceutics in Practice
PHM014 – Drug Delivery and Targeting
PHM3603 - Pharmaceutical Formulation III

PhD in Pharmaceutics

BSc(Hons) Human Biology

August 2016 – Present: Lecturer in Pharmaceutics at Aston University
October 2014 – July 2016: Lecturer in Physiology and Pharmacology at Coventry University College
February 2014 – June 2014: Lecturer in QbD at Aston University
January 2014 – July 2014: Postdoctoral Researcher at Aston University
September 2010 – December 2014: Studied PHD at Aston University
September 2006 – June 2010: Studied BSc (Hons) Human Biology at Uni. Huddersfield

Editorial Board Member for Research and Reviews: Drug Delivery

School Governor at Coppice Junior School
Part Time Lecturer at Coventry University College

In my role as a lecturer in pharmaceutics I intend to further advance research into in vitro drug absorption modelling. The aim is to benefit the drug development pipeline through an innovative application of novel approaches to permeability assays including genomic and metabolomic approaches not currently exploited. If successful this holds promise to reduce the number of medicinal products which fail at late stage clinical trials thus saving significant time and money. Concurrently, process development seeks to enhance and advance the technologies and methodologies used in existing drug development areas on a day to day basis. With a focus on formulation the techniques and technologies employed in current research are at the cutting edge of formulation development. Solubilisation and stabilisation of insoluble and sensitive drugs for the formulation of oral liquid medications represents one line of research while elsewhere, recent advances in 3D printing technology and intelligent formulation design are currently being exploited to produce novel solid dosage forms targeting a personalised medicine approach to drug development.

Biochemical Society
United Kingdom and Ireland Controlled Release Society (UKICRS)
Associate member of the Physiological Society

Craig Russell, Sumyra Begum, Yasar Hussain, Majad Hussain, David Huen, Ayesha S Rahman, Yvonne Perrie and Afzal R Mohammed. (2015) Paediatric Drug Development of Ramipril: Reformulation, In Vitro and In Vivo Evaluation. Journal of Drug Targeting

Craig Russell, Ayesha Rahman and Afzal R Mohammed (2013) Application of genomics, proteomics and metabolomics in drug discovery, development and clinic. Therapeutic Delivery. 4 (3) 395 - 413.

Book Chapters

Afzal R Mohammed and Craig A Russell (2012). Drug Development and Delivery. Integrated Foundations of Pharmacy – Pharmaceutics.

Afzal R. Mohammed, Amr M. ElShaer, Rhys J. Jones, Sheraz Khan, Craig A. Russell (2011) Drug Bioavailability and Gene Profiling: Challenges and Opportunities for Pharmaceutics and Personalised Medicine. Handbook of Personalized Medicine: Advances in Nanotechnology, Drug Delivery and Therapy.  

Other Publications
Affiong Iyire, Craig Russell, Clifford Bailey and Afzal R Mohammed (2014) Investigating buccal cell cultures to enhance assessment of transmucosal drug delivery. UKICRS newsletter.