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Multi–modal Neuroimaging

MRI - Multi–model Neuroimaging
Dr. N. Jade Thai, Prof Stefano Seri, Daniela Brazzo

The main aim of multi-modal neuroimaging studies have been to exploit the superior spatial resolution of fMRI and temporal resolution of EEG/MEG to improve our understanding of the neural mechanisms involved in visual processing, language development and attentional modulations of memory function. To effectively investigate these neuro cognitive processes we have developed novel integrated analysis of fMRI, MEG and EEG to elucidate the relationship between the different neurophysiological information provided by each neuroimaging modality.

We also have MRI compatible EEG system this technique allows us to record 2 different physiologies of brain activity simultaneously. EEG records the electrical activity and fMRI records brain heamodynamics therefore providing us with both high spatial and temporal resolution recordings of brain activity simultaneously. We use simultaneous EEG & fMRI for seizure localization in patients with epilepsy and understanding baseline resting state brain activity in a paediatric population (age 6-12).

We are also investigating the neural substrates of language development in children using simultaneous EEG & fMRI, from simple auditory processes involved in language to reading and speech production.