Paper published in the Journal of Materials Chemistry B
Bioactive Organic-Inorganic Hybrids with Improved Mechanical Performance
Human tissue including both soft tissue (e.g. skin) and hard tissue (e.g. bones) are continuously remodelled and regenerated throughout our lifetime. However, as we age our bodies’ ability to repair and regenerate significantly reduces. Healing in older adults can be particularly slow due to reduced cellular activity. As we age our bones become brittle and weaker and reduced bone density can be problematic for post-menopausal women. Consequently bone is the most widely transplanted material with the exception of blood. It is therefore very important to develop new and improved biomaterials for bone regeneration. Effective implant biomaterials can help tissue regenerate and significantly improve the quality of life of older adults in later life. Recently there has been a change in philosophy moving away from traditional materials (e.g. large metal plates that are inserted for life) towards developing new smart biomaterials that can help the body self-heal and eventually become absorbed and replaced by the body. Solid glass particles containing calcium and phosphorous (the main building blocks of bone) are now used widely clinically to treat small bone defects (e.g. orthopaedic bone grafting in non-load bearing sites, ossicular replacement, head and neck surgery, tooth root implants). The latest drive is to mimic nature by developing highly porous scaffolds which enhance blood flow and cell ingrowth to increase the rate of healing. However these materials are usually mechanically weak. Dr Richard Martin (ARCHA & EAS) in collaboration with colleagues at the Chinese Academy of Science have developed novel sol-gel polymer hybrids for bone replacement applications with vastly improved mechanical properties whilst still maintaining this porosity. A key feature of this work was ensuring that the organic and inorganic phases are strongly bonded together to stop the polymer from rapidly washing out from the hybrid which would reduce the strength. The work was recently published in the Journal of Materials Chemistry B; full details can be found at http://pubs.rsc.org/en/content/articlelanding/2014/tb/c4tb01776e#!divAbstract
The work was supported by ARCHA and a Royal Society/Natural Science Foundation of China international exchange grant (IE131323, 513111170).
ARCHA staff awarded European funding
Dr Carol Holland and a team from ARCHA including colleagues from psychology, biology and computer science have been awarded funding from the European 3 rd Health programme in collaboration with European colleagues from Spain, Portugal, Italy, the Netherlands and Poland. The project is to extend the work of the European Innovation Partnership on Active & Healthy Ageing in the subtopic of Frailty and Cognitive Decline. The title of the two year programme is “Frailty Management Optimisation through EIP AHA Commitments and Utilisation of Stakeholders input”, or “FOCUS”.
16th October 2013
The British Neuroscience Association and the Society of Biology West Midlands Branch are co-hosting the Dr Christopher Smith Memorial Lecture on the 16th October 2013 at Aston University. The lecture entitled "Reducing dementia risk through lifestyle changes: when to do what?" is being given by Professor Eef Hogervorst from the University of Loughborough.
Please register intention to attend lecture: email email@example.com noting your name and telephone number and indicate if you will be able to join us for refreshments (served 6.15 -7.15pm). For groups please provide total number in your party.
ARCHA “Speed Dating” Event
A research matching event in the style of “Speed Dating” took place on 13th December 2012. Open to all Aston research staff, it aimed to help bring together researchers from different areas with mutual interests in ageing. For further information please contact Wendy Overton. If you would like to discuss any possible research ideas, please contact the ARCHA Director, Dr Carol Holland.
Athletes Art Exhibition at Aston University
As part of Wellbeing Week 2012, a Wellbeing Fair open to all staff and students took place on 13th November 2012 at Aston.
There were a wide range of internal and external exhibitors including Sport and Recreation * DANU * the Health & Safety Unit *Quest Vitamins * Boots the Chemist *Alzheimer’s Society * Environment and Sustainability *AstBUG *Fairtrade Group * Counselling Service * MLK Chaplaincy * the Advice and Representation Centre (ARC) * the Hub * Optometry * Audiology * Aston Research Centre for Healthy Ageing (ARCHA) * Halcyon Medical Centre * Ruth Hickinbotham – Complementary Therapies *Catering and Conference Aston * Sustrans - all demonstrating the goods and services on offer locally to help you maintain a healthy lifestyle and sense of wellbeing.
A diverse range of other activities to promote health and wellbeing to staff and students also took place across the campus between 12th and 16th November 2012. See the Wellbeing posters or www.aston.ac.uk/staff/hr/wellbeing/ for details.
Aston University Challenging Perceptions of Ageing
Aston University hosted a photograph exhibition of veteran athletes who still compete at an international level.
Photographer, Alex Rotas, showcased her work at Aston University from 31st October, which featured photographs of competitive pole-vaulters, long jumpers and hurdlers in their 60s, 70s and 80s. The exhibition was designed to challenge potential stereotypes of older men and women within the UK.
The exhibition featured as part of Aston University’s Well-Being Week an initiative for staff which aimed to encourage healthier lifestyles at work. Aston Research Centre for Healthy Ageing (ARCHA) at Aston University, whose research focuses on older people’s wellbeing, also showcased their research at the event.
Dr Carol Holland, Director of ARCHA, said; “Alex’s work not only challenges perceptions of older people but also raises awareness of there are still very much abled older people in our society. Aston’s well-being week encourages staff to keep active and lead healthier working lives, we are happy that ARCHA can be involved with upcoming events. Alongside ARCHA’s focus on scientific research into Ageing we also explore the impact of changes in political and social environment on older people. ARCHA’s Ageing Lives cluster not only looks at impact of health and care policies, but also attitudes and beliefs towards ageing such as managing medicines and keeping active”.
For further information and to view the picture gallery visit alexrotasphotography.com.
Aston Study Reported in the Express
The news messages were:
1. Official figures may under estimated the use of anti-psychotics in dementia.
2. A medication review by a clinical pharmacist may be able to limit the prescribing of inappropriate anti-psychotics.
Ian Maidment, a senior lecturer in clinical pharmacy from Aston University, said: “The true scale of antipsychotic usage in dementia may be underestimated.”
Click HERE to read more.
Hot off the Press
The first journal article from the dementia project was published in the Medical Law Review. The article is called "He was like a zombie": Off-label prescription of antipsychotic drugs in dementia.
Click HERE to read the abstract.
ExtraCare in the news
ARCHA in the Public Service UK Science & Technology Magazine
View the article - Click on the middle tab and go to page 182.
European Year for Active Ageing
Fibre-optic implant could monitor wounds for infection
Fibre-optic implants could be used to monitor healing wounds for signs of infection if research by Aston University scientists is successful.
A team of researchers plans to study how to turn fibre-optic technology that can measure temperature and detect biological signs of disease into a device for implanting into a wound at surgery.
Doctors currently tend to check for infection by monitoring a patient’s temperature, but catching the problem before it has had a chance to affect the whole body could stop it becoming more serious.
Click HERE to read more.