Applied molecular biology

Key information

Duration: Duration times vary. Use the contact details below to enquire about this.

Location: Aston University, Birmingham

Fee: £550 per delegate

To register: Please complete an online application form.

The Biomedical Science top-up modules are for people who have a science degree but wish to pursue a career as a Biomedical Scientist. Prior to registering for any top-up modules you need to contact the Institute of Biomedical Science for advice about which modules you require: phone + 44 (0)20 7713 0214 or email mail@ibms.org

Further information: Contact LHS Admissions lhs_admissions@aston.ac.uk or telephone 0121 204 3000

Course content information: please contact Dr Corinne Spickett c.m.spickett@aston.ac.uk 

Aims of this module

To provide a basic introduction to the identity of genes, the nature and properties of nucleic acids and proteins and to explain how these molecules work together in gene expression and DNA replication. 

In this module, basic level chemistry will be used to explain how the structure of these biological macromolecules results in their activities. Where appropriate, experimental evidence will be provided to demonstrate how our current knowledge was derived.  Emphasis will be placed on the fact that molecular biology is still an experimental science.

Module content

Key biological molecules:
  • Structure of DNA, RNA and proteins
  • Different types of RNA: mRNA, tRNA, rRNA and snRNA
Nucleic acid function:
  • DNA replication
  • Gene structure in prokaryotes and eukaryotes
  • Gene expression and differences between prokaryotes and eukaryotes – the role of proteins and the different RNAs
The effect of mutations:

Protein function:
  • How a protein’s structure is responsible for its activity
  • How the amino acid sequence influences 3D structure
  • The relationship between gene sequence and protein activity
Analysis and application of molecular biology
  • Experimental evidence in support of some lecture material
  • Basic molecular biology – manipulation of nucleic acids
  • Basic Genetic Engineering – production of recombinant proteins and their uses