The damaged ocular surface can be treated with synthetic or semi-synthetic corneal replacements called keratoprostheses (KPro). Currently osteo-odonto-keratoprosthesis (OOKP) surgery remains the most successful approach for the keratinised eye. This device uses a lamina prepared from a single-root tooth with surrounding bone sawn from the patient's jawbone, into which a PMMA optic is cemented. Drawbacks with the OOKP surgery are that it is very time consuming and oral structures are sacrificed. To address these problems the Biomaterials Research Unit has an active development programme seeking a synthetic alternative to the patient’s own tooth and bone.